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Fig. 3 | BMC Genomic Data

Fig. 3

From: Differential lung gene expression changes in C57BL/6 and DBA/2 mice carrying an identical functional Mx1 gene reveals crucial differences in the host response

Fig. 3

Volcano plots of differentially expressed genes (DEGs). A B6-Mx1r/r at day 3 p.i. versus mock-infected B6-Mx1r/r mice. B B6-Mx1r/r at day 5 p.i. versus mock-infected B6-Mx1r/r mice. C D2-Mx1r/r at day 3 p.i. versus mock-infected D2-Mx1r/r mice. D D2-Mx1r/r at day 5 p.i. versus mock-infected D2-Mx1r/r mice. E D2-Mx1r/r at day 3 p.i. versus B6-Mx1r/r at day 3 p.i. infected mice. F D2-Mx1r/r at day 5 p.i. versus B6-Mx1r/r at day 5 p.i. infected mice. Y-axis: -log10 multiple testing adjusted p-values, x-axis: log2 fold change. DEGs are colored red, and the top 20 up- and down-regulated (by log-fold change) DEGs are labeled. Blue: genes with an adjusted p-value < 0.05. Yellow: genes with an absolute log2-fold change > 1. Grey: not significant (NS)

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